{"data":{"id":203482,"slug":"postdoktor-i-kromatindynamik-vid-extrem-uttorkningstolerans","type":"job","title":"Postdoctoral Researcher in Chromatin Dynamics at Extreme Desiccation Tolerance","description":"Department of Plant Biology\nAbout the Position\nWe are seeking a highly motivated postdoctoral researcher to join our research group at the Swedish University of Agricultural Sciences (SLU) in Uppsala to investigate how plant cells reorganize their cell nuclei and gene regulatory systems to survive extreme environmental conditions. Certain organisms can survive the loss of nearly all cellular water by entering a state of suspended animation, known as anhydrobiosis. Orthodox plant seeds and so-called resurrection plants\u2014plants with extreme desiccation tolerance\u2014are remarkable examples: differentiated vegetative cells can tolerate severe drying and subsequently resume normal growth after rehydration. How a differentiated cell can undergo such an extreme physiological transition while preserving genome integrity, cellular identity, and the ability to reactivate gene expression remains not fully understood. The project will investigate changes in chromatin and transcription in connection with the transition to the desiccated state and recovery from it, using plants with extreme desiccation tolerance and possibly complementary plant systems. We are particularly interested in understanding whether desiccation is accompanied by the establishment of a specialized and reversible chromatin state, how this state contributes to protecting the genome and halting transcription, and how normal organization of the cell nucleus and normal gene expression are restored after rehydration.\nThis position is affiliated with the research group led by Dr Stefanie Rosa at the Department of Plant Biology, Swedish University of Agricultural Sciences (SLU), Uppsala. Our group studies how the organization and dynamics of chromatin affect the regulation and stability of plant genomes (https:\/\/www.slu.se\/en\/profilepages\/r\/stefanie-rosa\/).\nThe project offers great freedom to develop a new research direction at the intersection of chromatin biology, transcription, cell biology, and extreme stress tolerance. The successful candidate will have access to advanced microscopy infrastructure at Uppsala BioCenter and work in a collaborative research environment encompassing plant cell biology, genetics, genomics, and developmental biology.\nYour Background\nWe are seeking a creative and highly motivated researcher with a PhD in plant biology, molecular biology, cell biology, genetics, genomics, or a related field. Previous experience with molecular biological methods, cell biology, and plant developmental biology is advantageous. Strong ability to communicate orally and in writing in English is required. You should also have the ability to conduct independent research, take initiative, formulate relevant scientific questions, and collaborate with other researchers. The position is intended for a junior researcher, and we are primarily seeking individuals who completed their PhD no more than three years ago. If there are special circumstances, the PhD may have been completed earlier. Special circumstances include leave due to illness, parental leave, positions of trust within trade union organizations, military service, or other similar circumstances, as well as clinical practice or practice\/positions relevant to the field.\nAbout Us\nThe Department's research is primarily focused on plants, but other organisms such as viruses, bacteria, fungi, insects, yeast cells, and even human cells are also studied. Our main research areas include interactions between plants and microorganisms and other forms of stress; biotechnology and metabolic engineering; plant growth and development; regulation of gene expression; population genetics, genome analysis, and development of plant breeding systems. The organisms used include model organisms such as Arabidopsis thaliana, Physcomitrella, tobacco, and yeast, as well as crops such as rapeseed, short-rotation willow (Salix), potato, barley, rye, wheat, and cassava.\nThe Department is responsible for basic and advanced courses in general and molecular genetics, genetic engineering, cell biology, plant physiology, gene expression, plant breeding, plant biochemistry, and biotechnology, as well as molecular interactions between plants and pathogens. Additionally, the Department participates in several other biology courses together with other departments. The courses are part of master's programs in biotechnology and natural resources and in educational programs for students in agronomy and landscape architecture, but most courses are also open to external students.\nLink to the Department: https:\/\/www.slu.se\/om-slu\/organisation\/institutioner\/vaxtbiologi-skogsgenetik\/?gad_source=1&gad_campaignid=21086656031&gclid=Cj0KCQjw79nUBhCgARIsADSHka20iV0H7QlBK34j0DkJW5t45CE5ipbpdxMtH4AYC0FW4I9PNKBAMZ8aAsNMEALw_wcB.\nLearn more about our benefits and what it is like to work at SLU at https:\/\/www.slu.se\/om-slu\/jobba-pa-slu\/\nLocation:\nUppsala.\nEmployment Type:\nFixed-term position for 24 months, with possible extension.\nFull-time Position:\n100%.\nStart Date:\nBy agreement.\nApplication:\nWelcome to submit your application by September 30, 2026. Submit your application by clicking the button below. The following documents must be attached to your application: Your application should include (1) a cover letter describing your research interests and relevant experience, (2) a CV with a complete list of publications, and (3) contact information for two to three referees.\nTrade Union Representatives:\nhttps:\/\/internt.slu.se\/min-anstallning\/facket\/kontaktpersoner\/\nSwedish University of Agricultural Sciences (SLU) has a key role in development for sustainable life, grounded in science and education. Through our focus on interactions between humans, animals, and ecosystems and responsible use of natural resources, we contribute to sustainable societal development and good living conditions on our planet. Our main offices are in Alnarp, Ume\u00e5, and Uppsala, but operations also take place at research stations, experimental farms, and educational centers throughout the country. SLU has over 4,000 employees, 6,000 students and doctoral students, and a turnover of over 4.5 billion SEK. The University is investing in attractive environments on its campus areas. We work toward a gender-equal and inclusive work environment where open dialogue between people with different experiences forms the foundation for scientific rigor, creativity, and development. We therefore welcome people with different backgrounds and perspectives to apply for this position.","language":"sv","is_translated":true,"title_original":"Postdoktor i kromatindynamik vid extrem uttorkningstolerans","description_original":"Institutionen f\u00f6r v\u00e4xtbiologi\nOm jobbet\nVi s\u00f6ker en mycket motiverad postdoktoral forskare som vill ansluta sig till v\u00e5r forskargrupp vid Sveriges lantbruksuniversitet (SLU) i Uppsala f\u00f6r att unders\u00f6ka hur v\u00e4xtceller omorganiserar sina cellk\u00e4rnor och genreglerande system f\u00f6r att \u00f6verleva extrema milj\u00f6f\u00f6rh\u00e5llanden. Vissa organismer kan \u00f6verleva f\u00f6rlusten av n\u00e4stan allt cellul\u00e4rt vatten genom att g\u00e5 in i ett tillst\u00e5nd av avstannad livsaktivitet, s\u00e5 kallad anhydrobios. Ortodoxa v\u00e4xtfr\u00f6n och s\u00e5 kallade resurrection plants, v\u00e4xter med extrem uttorkningstolerans, utg\u00f6r anm\u00e4rkningsv\u00e4rda exempel: differentierade vegetativa celler kan t\u00e5la kraftig uttorkning och d\u00e4refter \u00e5teruppta normal tillv\u00e4xt efter \u00e5terfuktning. Hur en differentierad cell kan genomg\u00e5 en s\u00e5 extrem fysiologisk omst\u00e4llning och samtidigt bevara genomets integritet, sin cellul\u00e4ra identitet och f\u00f6rm\u00e5gan att \u00e5teraktivera genuttryck \u00e4r fortfarande inte helt klarlagt. Projektet kommer att unders\u00f6ka f\u00f6r\u00e4ndringar i kromatin och transkription i samband med \u00f6verg\u00e5ngen till det uttorkade tillst\u00e5ndet och \u00e5terh\u00e4mtningen fr\u00e5n detta, med hj\u00e4lp av v\u00e4xter med extrem uttorkningstolerans och eventuellt kompletterande v\u00e4xtsystem. Vi \u00e4r s\u00e4rskilt intresserade av att f\u00f6rst\u00e5 om uttorkning \u00e5tf\u00f6ljs av etableringen av ett specialiserat och reversibelt kromatintillst\u00e5nd, hur detta tillst\u00e5nd bidrar till att skydda genomet och stoppa transkriptionen samt hur normal organisation av cellk\u00e4rnan och normalt genuttryck \u00e5terst\u00e4lls efter \u00e5terfuktning.\nTj\u00e4nsten \u00e4r knuten till den forskargrupp som leds av Dr Stefanie Rosa vid Institutionen f\u00f6r v\u00e4xtbiologi, Sveriges lantbruksuniversitet (SLU), Uppsala. V\u00e5r grupp studerar hur kromatinets organisation och dynamik p\u00e5verkar regleringen och stabiliteten av v\u00e4xters genom (https:\/\/www.slu.se\/en\/profilepages\/r\/stefanie-rosa\/).\nProjektet erbjuder stor frihet att utveckla en ny forskningsinriktning i gr\u00e4nslandet mellan kromatinbiologi, transkription, cellbiologi och tolerans mot extrem stress. Den framg\u00e5ngsrika kandidaten kommer att ha tillg\u00e5ng till avancerad mikroskopiinfrastruktur vid Uppsala BioCenter och arbeta i en samarbetsinriktad forskningsmilj\u00f6 som omfattar v\u00e4xtcellbiologi, genetik, genomik och utvecklingsbiologi.\nDin bakgrund\nVi s\u00f6ker en kreativ och mycket motiverad forskare med doktorsexamen inom v\u00e4xtbiologi, molekyl\u00e4rbiologi, cellbiologi, genetik, genomik eller ett n\u00e4rliggande omr\u00e5de. Tidigare erfarenhet av molekyl\u00e4rbiologiska metoder, cellbiologi och v\u00e4xters utvecklingsbiologi \u00e4r meriterande. God f\u00f6rm\u00e5ga att kommunicera muntligt och skriftligt p\u00e5 engelska \u00e4r ett krav. Du b\u00f6r \u00e4ven ha f\u00f6rm\u00e5ga att bedriva sj\u00e4lvst\u00e4ndig forskning, ta initiativ, formulera relevanta vetenskapliga fr\u00e5gest\u00e4llningar och samarbeta med andra forskare. Anst\u00e4llningen \u00e4r avsedd f\u00f6r en junior forskare och vi s\u00f6ker fr\u00e4mst personer som avlagt doktorsexamen f\u00f6r h\u00f6gst tre \u00e5r sedan. Om det finns s\u00e4rskilda sk\u00e4l kan s\u00e5dan examen ha avlagts tidigare. Med s\u00e4rskilda sk\u00e4l avses ledighet p\u00e5 grund av sjukdom, f\u00f6r\u00e4ldraledighet, f\u00f6rtroendeuppdrag inom fackliga organisationer, tj\u00e4nstg\u00f6ring inom totalf\u00f6rsvaret, eller andra liknande omst\u00e4ndigheter samt klinisk tj\u00e4nstg\u00f6ring eller f\u00f6r \u00e4mnesomr\u00e5det relevant tj\u00e4nstg\u00f6ring\/uppdrag.\nOm oss\nInstitutionens forskning \u00e4r huvudsakligen inriktad p\u00e5 v\u00e4xter, men \u00e4ven andra organismer s\u00e5som virus, bakterier, svampar, insekter, j\u00e4stceller och till och med m\u00e4nskliga celler studeras. V\u00e5ra huvudsakliga forskningsomr\u00e5den \u00e4r samspelet mellan v\u00e4xter och mikroorganismer samt andra former av stress; bioteknik och metabol ingenj\u00f6rskonst; v\u00e4xters tillv\u00e4xt och utveckling; reglering av genuttryck; populationsgenetik, genomanalys och utveckling av v\u00e4xtf\u00f6r\u00e4dlingssystem. De arter som anv\u00e4nds omfattar modellorganismer s\u00e5som Arabidopsis thaliana, Physcomitrella, tobak och j\u00e4st, samt gr\u00f6dor s\u00e5som raps, korgpil (Salix), potatis, korn, r\u00e5g, vete och kassava.\nInstitutionen ansvarar f\u00f6r grundl\u00e4ggande och avancerade kurser inom allm\u00e4n och molekyl\u00e4r genetik, genteknik, cellbiologi, v\u00e4xtfysiologi, genuttryck, v\u00e4xtf\u00f6r\u00e4dling, v\u00e4xtbiokemi och bioteknik samt molekyl\u00e4ra interaktioner mellan v\u00e4xter och patogener. D\u00e4rut\u00f6ver medverkar institutionen i flera andra biologikurser tillsammans med andra institutioner. Kurserna ing\u00e5r i masterprogrammen i bioteknik och naturresurser samt i utbildningsprogram f\u00f6r studenter inom agronomi och landskapsarkitektur, men de flesta kurser \u00e4r \u00e4ven \u00f6ppna f\u00f6r externa studenter.\nL\u00e4nk till institutionens https:\/\/www.slu.se\/om-slu\/organisation\/institutioner\/vaxtbiologi-skogsgenetik\/?gad_source=1&gad_campaignid=21086656031&gclid=Cj0KCQjw79nUBhCgARIsADSHka20iV0H7QlBK34j0DkJW5t45CE5ipbpdxMtH4AYC0FW4I9PNKBAMZ8aAsNMEALw_wcB.\nL\u00e4s mer om v\u00e5ra f\u00f6rm\u00e5ner och hur det \u00e4r att jobba vid SLU p\u00e5 https:\/\/www.slu.se\/om-slu\/jobba-pa-slu\/\nPlacering:\nUppsala.\nAnst\u00e4llningsform:\nTidsbegr\u00e4nsad anst\u00e4llning 24 m\u00e5nader, med ev. m\u00f6jlighet till f\u00f6rl\u00e4ngning.\nOmfattning:\n100%.\nTilltr\u00e4de:\nEnligt \u00f6verenskommelse.\nAns\u00f6kan:\nV\u00e4lkommen med din ans\u00f6kan senast den 30 september 2026. Du skickar in din ans\u00f6kan genom att klicka p\u00e5 knappen nedan. F\u00f6ljande dokument ska bifogas ans\u00f6kan: Ans\u00f6kan ska inneh\u00e5lla (1) ett motivationsbrev d\u00e4r du beskriver dina forskningsintressen och relevanta erfarenheter, (2) ett CV med fullst\u00e4ndig publikationslista samt (3) kontaktuppgifter till tv\u00e5 till tre referenspersoner.\nFackliga kontaktpersoner:\nhttps:\/\/internt.slu.se\/min-anstallning\/facket\/kontaktpersoner\/\nSveriges lantbruksuniversitet (SLU) har en nyckelroll i utvecklingen f\u00f6r h\u00e5llbart liv, grundad i vetenskap och utbildning. Genom v\u00e5rt fokus p\u00e5 samspelen mellan m\u00e4nniska, djur och ekosystem och ett ansvarsfullt brukande av naturresurserna bidrar vi till en h\u00e5llbar samh\u00e4llsutveckling och goda livsvillkor p\u00e5 v\u00e5r planet. Huvudorter \u00e4r Alnarp, Ume\u00e5 och Uppsala, men verksamhet bedrivs ocks\u00e5 p\u00e5 forskningsstationer, f\u00f6rs\u00f6ksparker och utbildningsorter i hela landet. SLU har drygt 4000 medarbetare, 6000 studenter och forskarstuderande och en oms\u00e4ttning p\u00e5 \u00f6ver 4,5 miljarder kronor. Universitetet satsar p\u00e5 attraktiva milj\u00f6er p\u00e5 sina campusomr\u00e5den. Vi arbetar f\u00f6r en j\u00e4mst\u00e4lld och inkluderande arbetsmilj\u00f6 d\u00e4r \u00f6ppna samtal mellan m\u00e4nniskor med olika erfarenheter l\u00e4gger grunden f\u00f6r vetenskaplighet, kreativitet och utveckling. Vi v\u00e4lkomnar d\u00e4rf\u00f6r personer med olika bakgrunder och perspektiv att s\u00f6ka den aktuella anst\u00e4llningen.","price":null,"currency":"SEK","status":"active","noindex":true,"location":{"address":null,"full_address":null,"city":"Uppsala","country":"SE","latitude":59.8520701,"longitude":17.7188369},"metadata":{"region":"Uppsala l\u00e4n","duration":"6 m\u00e5nader eller l\u00e4ngre","employer":"Sveriges Lantbruksuniversitet","postcode":"75007","positions":1,"profession":"Biolog","salary_type":"Fast m\u00e5nads- vecko- eller timl\u00f6n","employer_url":"https:\/\/www.slu.se\/","scope_of_work":"100\u2013100 %","working_hours":"Heltid","contact_person":"Stefanie Rosa","employment_type":"full_time","occupation_field":"Naturvetenskap","employer_workplace":"Sveriges Lantbruksuniversitet (SLU)","experience_required":true,"employment_type_label":"Vanlig anst\u00e4llning"},"user_id":null,"is_sponsored":false,"views_count":0,"ai_views_count":9,"bot_views_count":2,"ai_vendor_counts":{"meta":2,"other":2,"openai":3,"anthropic":2},"visibility":"public","submission_source":null,"submission_ai_name":null,"has_owner_email":true,"can_contact_owner":true,"phone":null,"owner_email":"Stefanie.Rosa@slu.se","images":[],"published_at":"2026-09-09T12:55:41+00:00","expires_at":"2026-09-30T23:59:59+00:00","created_at":"2026-09-10T04:05:44+00:00","updated_at":"2026-09-16T03:08:01+00:00"}}