{"data":{"id":222927,"slug":"postdoktor-inom-berakningskemi-och-strukturbaserad-lakemedelsdesign","type":"job","title":"Postdoctoral Researcher in Computational Chemistry and Structure-Based Drug Design","description":"Would you like to work with drug development, supported by competent and friendly colleagues in an international environment? Would you like an employer that invests in sustainable employee relations and offers secure, favorable working conditions? We welcome your application for a postdoctoral position at Uppsala University.\nThe Department of Cell and Molecular Biology is divided into seven research programs, all focusing on different areas within cell and molecular biology: computational biology and bioinformatics, microbiology and immunology, molecular biology, molecular biophysics, molecular evolution, molecular systems biology, and structural biology. The scientific foundation of our work lies in biology, but our research overlaps with other areas such as medicine, computer science, mathematics, chemistry, engineering, and physics. The department has over 200 employees with around 60 doctoral students. Learn more about the department's work at https:\/\/icm.uu.se.\nThe position will be placed in Jens Carlsson's research group within the Computational Biology and Bioinformatics program. Jens Carlsson's research focuses on computational modeling of proteins with particular emphasis on G-protein coupled receptors. Jens Carlsson's group uses modeling to understand how receptors function at the molecular level and develops methods to identify drug candidates, often in collaboration with experimental research groups. It is an international research team that is also part of Science for Life Laboratory (http:\/\/www.scilifelab.se\/). More information about the group's research can be found on its website (www.carlssonlab.org).\nResponsibilities\nThe project is aimed at studying how drugs bind to G-protein coupled receptors using computational models. The project's main goal is to understand how small molecules affect receptors by studying them at the molecular level and using this knowledge to develop new strategies for drug development. The project also includes close collaborations with experimental research groups in pharmacology and structural biology.\nQualification Requirements\nDoctoral degree in computational chemistry or a foreign degree assessed as equivalent to a doctoral degree in the same field. The degree must be completed no later than the time the employment decision is made. Preferably, the degree should have been obtained within the last three years. When calculating the three-year period, the starting point is the final application deadline. If there are special reasons, such a degree may have been obtained earlier. Special reasons include leave due to illness, parental leave, trust assignments within trade union organizations, etc.\nVery good knowledge of computational chemistry with extensive experience in molecular dynamics simulations for G-protein coupled receptors is required. The work requires good written and oral proficiency in English as the project is conducted in an international environment.\nWe place great emphasis on personal qualities such as good teamwork ability, motivation, and independence.\nDesired\/Meriting Qualifications\nPrevious experience from the Department of Cell and Molecular Biology is strongly meriting. Previous experience in modeling of aminergic receptors, machine learning, and molecular docking is also meriting.\nAbout the Position\nThe employment is fixed-term for two years according to a central collective agreement. The position is full-time. Start date February 1, 2027, or by agreement. Location: Uppsala\nInformation about the position is provided by: Jens Carlsson, jens.carlsson@icm.uu.se, Tel: 072 227 7976.\nWelcome to submit your application by October 5, 2026, UFV-PA 2026\/2736.\nUppsala University is a broad research university with strong international standing. The ultimate goal is to conduct education and research of the highest quality and relevance to make a difference in society. Our most important asset is all 7,500 employees and 53,000 students who, with curiosity and commitment, make Uppsala University one of the country's most exciting workplaces.\nLearn more about our benefits and what it is like to work at Uppsala University\nhttps:\/\/uu.se\/om-uu\/jobba-hos-oss\/\nThe employment may be subject to security vetting. Security vetting is a condition for employment; applicants must be approved.\nWe decline offers of recruitment and advertising assistance.\nApplications are received through Uppsala University's recruitment system.\nTrade union representatives: Saco-S - saco-s@uu.se, Seko - seko@uadm.uu.se, ST (OFR\/S) - ofr@uu.se","language":"sv","is_translated":true,"title_original":"Postdoktor inom ber\u00e4kningskemi och strukturbaserad l\u00e4kemedelsdesign","description_original":"Vill du arbeta med l\u00e4kemedelsutveckling, med st\u00f6d av kompetenta och trevliga kollegor i en internationell milj\u00f6? Vill du ha en arbetsgivare som satsar p\u00e5 ett h\u00e5llbart medarbetarskap och erbjuder trygga, f\u00f6rm\u00e5nliga arbetsvillkor? V\u00e4lkommen att s\u00f6ka anst\u00e4llning som postdoktor p\u00e5 Uppsala universitet.\nInstitutionen f\u00f6r cell- och molekyl\u00e4rbiologi \u00e4r indelad i sju forskningsprogram som alla fokuserar p\u00e5 olika omr\u00e5den inom cell- och molekyl\u00e4rbiologi: ber\u00e4kningsbiologi och bioinformatik, mikrobiologi och immunologi, molekyl\u00e4rbiologi, molekyl\u00e4r biofysik, molekyl\u00e4r evolution, molekyl\u00e4r systembiologi och strukturbiologi. Den vetenskapliga grunden till vad vi g\u00f6r ligger i biologi, men v\u00e5r forskning \u00f6verlappar med andra omr\u00e5den s\u00e5som medicin, datavetenskap, matematik, kemi, ingenj\u00f6rsvetenskaper och fysik. Institutionen har \u00f6ver 200 anst\u00e4llda med runt 60 doktorander. L\u00e4s g\u00e4rna mer om verksamhetens arbete p\u00e5 https:\/\/icm.uu.se.\nTj\u00e4nsten kommer att vara placerad i Jens Carlssons forskargrupp p\u00e5 programmet f\u00f6r Ber\u00e4kningsbiologi och Bioinformatik. Jens Carlssons forskning fokuserar p\u00e5 datormodellering av proteiner med s\u00e4rskilt fokus p\u00e5 G-proteinkopplade receptorer. Jens Carlssons grupp anv\u00e4nder modellering f\u00f6r att f\u00f6rst\u00e5 hur receptorer fungerar p\u00e5 molekyl\u00e4r niv\u00e5 och utvecklar metoder f\u00f6r att identifiera l\u00e4kemedelskandidater, ofta i samarbete med experimentella forskargrupper. Det \u00e4r ett internationellt forskningsteam som ocks\u00e5 \u00e4r en del av Science for Life Laboratory (http:\/\/www.scilifelab.se\/). Mer information om gruppens forskning finns p\u00e5 dess hemsida (www.carlssonlab.org).\nArbetsuppgifter \u00a0\nProjektet \u00e4r inriktat p\u00e5 att studera hur l\u00e4kemedel binder till G-proteinkopplade receptorer med hj\u00e4lp av datormodeller. Projektets huvudm\u00e5l \u00e4r att f\u00f6rst\u00e5 hur sm\u00e5 molekyler p\u00e5verkar receptorer genom att studera dem p\u00e5 molekyl\u00e4r niv\u00e5 och anv\u00e4nda denna kunskap f\u00f6r att utveckla nya strategier f\u00f6r l\u00e4kemedelsutveckling. Projektet innefattar ocks\u00e5 n\u00e4ra samarbeten med experimentella forskargrupper inom farmakologi och strukturbiologi.\nKvalifikationskrav\nDoktorsexamen i ber\u00e4kningskemi eller en utl\u00e4ndsk examen som bed\u00f6ms motsvara doktorsexamen inom samma omr\u00e5de. Examen ska vara uppfyllt senast vid tidpunkten d\u00e5 anst\u00e4llningsbeslutet fattas. Fr\u00e4mst b\u00f6r den komma ifr\u00e5ga som har avlagt examen f\u00f6r h\u00f6gst tre \u00e5r sedan. Vid ber\u00e4kning av ramtiden om tre \u00e5r \u00e4r utg\u00e5ngspunkten sista ans\u00f6kningsdag. Om det finns s\u00e4rskilda sk\u00e4l kan s\u00e5dan examen ha avlagts tidigare. Med s\u00e4rskilda sk\u00e4l avses ledighet p\u00e5 grund av sjukdom, f\u00f6r\u00e4ldraledighet, f\u00f6rtroendeuppdrag inom fackliga organisationer, etc.\nMycket goda kunskaper inom ber\u00e4kningskemi med omfattande erfarenhet av molekyldynamiksimuleringar f\u00f6r G-proteinkopplade receptorer \u00e4r ett krav. Arbetet kr\u00e4ver goda skriftliga och muntliga kunskaper i engelska d\u00e5 projektet genomf\u00f6rs i en internationell milj\u00f6.\nVi l\u00e4gger stor vikt vid personliga egenskaper s\u00e5som god samarbetsf\u00f6rm\u00e5ga, motivation och sj\u00e4lvst\u00e4ndighet.\n\u00d6nskv\u00e4rt\/meriterande i \u00f6vrigt\nTidigare erfarenhet fr\u00e5n institutionen f\u00f6r cell- och molekyl\u00e4rbiologi \u00e4r starkt meriterande. Tidigare erfarenheter inom modellering av aminerga receptorer, maskininl\u00e4rning och molekyl\u00e4r dockning \u00e4r ocks\u00e5 meriterande.\nOm anst\u00e4llningen\u00a0\nAnst\u00e4llningen \u00e4r tidsbegr\u00e4nsad i tv\u00e5 \u00e5r enligt centralt kollektivavtal. Omfattningen \u00e4r heltid. Tilltr\u00e4de 2027-02-01 eller enligt \u00f6verenskommelse. Placeringsort: Uppsala\nUpplysningar\u00a0om anst\u00e4llningen l\u00e4mnas av:\u00a0Jens Carlsson, jens.carlsson@icm.uu.se, Tel: 072 227 7976.\nV\u00e4lkommen med din ans\u00f6kan senast den 5 oktober 2026, UFV-PA 2026\/2736.\nUppsala universitet \u00e4r ett brett forskningsuniversitet med stark internationell st\u00e4llning. Det yttersta m\u00e5let \u00e4r att bedriva utbildning och forskning av h\u00f6gsta kvalitet och relevans f\u00f6r att g\u00f6ra skillnad i samh\u00e4llet. V\u00e5r viktigaste tillg\u00e5ng \u00e4r alla 7 500 anst\u00e4llda och 53 000 studenter som med nyfikenhet och engagemang g\u00f6r Uppsala universitet till en av landets mest sp\u00e4nnande arbetsplatser.\nL\u00e4s mer om v\u00e5ra f\u00f6rm\u00e5ner och hur det \u00e4r att jobba inom Uppsala universitet\nhttps:\/\/uu.se\/om-uu\/jobba-hos-oss\/\nAnst\u00e4llningen kan komma att s\u00e4kerhetspr\u00f6vas. Vid s\u00e4kerhetspr\u00f6vning \u00e4r en f\u00f6ruts\u00e4ttning f\u00f6r anst\u00e4llning att s\u00f6kande blir godk\u00e4nd.\nVi undanber oss erbjudanden om rekryterings- och annonseringshj\u00e4lp.\nAns\u00f6kan tas emot i Uppsala universitets rekryteringssystem.\nFackliga f\u00f6retr\u00e4dare: Saco-S - saco-s@uu.se, Seko - seko@uadm.uu.se, ST (OFR\/S) - ofr@uu.se","available_locales":["en"],"price":null,"currency":"SEK","status":"active","noindex":true,"location":{"address":"Box 256","full_address":null,"city":"Uppsala","country":"SE","latitude":59.8520701,"longitude":17.7188369},"metadata":{"region":"Uppsala l\u00e4n","duration":"6 m\u00e5nader eller l\u00e4ngre","employer":"Uppsala Universitet","postcode":"75105","positions":1,"profession":"Postdoktor\/Postdoc","salary_type":"Fast m\u00e5nads- vecko- eller timl\u00f6n","employer_url":"http:\/\/www.uu.se\/jobb\/","scope_of_work":"100\u2013100 %","working_hours":"Heltid","employment_type":"full_time","occupation_field":"Pedagogik","employer_workplace":"Uppsala universitet, Institutionen f\u00f6r cell- och molekyl\u00e4rbiologi","translation_status":"done","experience_required":true,"employment_type_label":"Vanlig anst\u00e4llning"},"user_id":null,"is_sponsored":false,"views_count":0,"ai_views_count":1,"bot_views_count":0,"ai_vendor_counts":{"anthropic":1},"visibility":"public","submission_source":null,"submission_ai_name":null,"has_owner_email":true,"can_contact_owner":true,"phone":"072 227 7976","owner_email":"jens.carlsson@icm.uu.se","images":[],"published_at":"2026-09-21T14:38:10+00:00","expires_at":"2026-10-05T23:59:59+00:00","created_at":"2026-09-22T03:20:06+00:00","updated_at":"2026-09-22T03:45:09+00:00"}}